Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Robert Sean Leonard Dr. James Wilson Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Olivia Wilde Thirteen, Dr. Remy Hadley Actor Vinessa Shaw Dr. Kelly Benedict Guest Star Zachary Knighton Billy Guest Star Erin Cahill Margaret McPherson Guest Star Eddie Matos Felipe Guest Star Jamie Tompkins Brandi Guest Star Kayla Colbert Rachel Cuddy Guest Star Rylie Colbert Rachel Cuddy Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer David Straiton Director Peter Blake Writer