Hugh Laurie Dr. Gregory House Actor Robert Sean Leonard Dr. James Wilson Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Odette Annable Dr. Jessica Adams Actor Charlyne Yi Dr. Chi Park Actor Olivia Wilde Thirteen, Dr. Remy Hadley Guest Star Jennifer Crystal Foley Rachel Taub Guest Star James Le Gros Oliver Guest Star Karolina Wydra Dominika House Guest Star Patrick O'Connor Dr. Frankel Guest Star Patrick Quinlan Patient 1 Guest Star Zena Grey Ruby Guest Star Diane Baker Blythe House Guest Star Andre Braugher Dr. Darryl Nolan Guest Star Anne Dudek Dr. Amber Volakis Guest Star Jennifer Morrison Dr. Allison Cameron Guest Star Kal Penn Dr. Lawrence Kutner Guest Star Amber Tamblyn Martha M. Masters Guest Star Jaclyn Jonet Amy Guest Star Patrick Price Nurse Jeffrey Sparkman Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer, Director, Writer Bryan Singer Executive Producer Peter Blake Writer Eli Attie Writer