Dominic Purcell Lincoln Burrows Actor Wentworth Miller Michael Scofield Actor Amaury Nolasco Fernando Sucre Actor Robert Knepper Theodore "T-Bag" Bagwell Actor Wade Williams Capt. Brad Bellick Actor Chris Vance James Whistler Actor Danay Garcia Sofia Lugo Actor Jodi Lyn O'Keefe Gretchen Morgan Actor William Fichtner Special Agent Alexander Mahone Actor Michael Rapaport Donald Self Actor Sarah Wayne Callies Dr. Sara Tancredi Actor Kathleen Quinlan Christina Rose Scofield Guest Star Rockmond Dunbar C-Note Guest Star Leon Russom General Jonathan Krantz Guest Star Ted King Downey Guest Star Raphael Sbarge Ralph Becker Guest Star William Mapother FBI Agent Chris Franco Guest Star Reno Wilson Agent Wilson Wright Guest Star Barbara Eve Harris FBI Agent Felicia Lang Guest Star Jennifer Kern Allison Hale Guest Star Andrew Borba ER Doctor Guest Star Tony Armatrading Soloman Okella Guest Star Paul Adelstein Paul Kellerman Guest Star Rod Britt Chaplain Guest Star Patrick Faucette Gunman Guest Star Kevin Scott Allen Inmate Guest Star Martinez Miami Cop #1 Guest Star Bruno Gunn Miami Cop #2 Guest Star Mark Berry Detective #1 Guest Star Marty Adelstein Executive Producer Paul Scheuring Executive Producer Dawn Parouse Executive Producer Matt Olmstead Executive Producer Brett Ratner Executive Producer