Paul Abbott Creator William H. Macy Frank Gallagher Actor Emmy Rossum Fiona Gallagher Actor Ethan Cutkosky Carl Gallagher Actor Shanola Hampton Veronica Actor Steve Howey Kev Actor Emma Kenney Debbie Gallagher Actor Cameron Monaghan Ian Gallagher Actor Jeremy Allen White Lip Gallagher Actor Emily Bergl Sammi Gallagher Actor Noel Fisher Mickey Milkovich Actor Dermot Mulroney Sean Pierce Guest Star Sherilyn Fenn Queenie Guest Star Anne Gee Byrd Fern Guest Star Kyle Davis Damon Guest Star Isidora Goreshter Svetlana Guest Star Jeff Kober Jupiter Guest Star Peter Macon Dominique's father Guest Star Jeff Pierre Caleb Guest Star Alan Rosenberg Professor Youens Guest Star Jaylen Barron Dominique Guest Star