Peter Krause Nate Fisher Jr. Actor Rachel Griffiths Brenda Chenowith Actor Richard Jenkins Nathaniel Fisher Sr. Actor Frances Conroy Ruth Fisher Actor Michael C. Hall David Fisher Actor Lauren Ambrose Claire Fisher Actor Freddy Rodríguez Federico Diaz Actor Mathew St. Patrick Keith Charles Actor James Cromwell George Sibley Actor Justina Machado Vanessa Diaz Actor Jeremy Sisto Billy Chenowith Guest Star Joanna Cassidy Margaret Chenowith Guest Star Tina Holmes Maggie Sibley Guest Star Anne Ramsay Guest Star Chris Messina Guest Star C.J. Sanders Guest Star Peter Macdissi Olivier Castro-Staal Guest Star Kendre Berry Guest Star Christine Tucci Guest Star Abby Brammell Guest Star Alan Ball Executive Producer