Peter Krause Nate Fisher Jr. Actor Rachel Griffiths Brenda Chenowith Actor Richard Jenkins Nathaniel Fisher Sr. Actor Frances Conroy Ruth Fisher Actor Michael C. Hall David Fisher Actor Lauren Ambrose Claire Fisher Actor Freddy Rodríguez Federico Diaz Actor Mathew St. Patrick Keith Charles Actor James Cromwell George Sibley Actor Justina Machado Vanessa Diaz Actor Jeremy Sisto Billy Chenowith Guest Star Joanna Cassidy Margaret Chenowith Guest Star Tina Holmes Maggie Sibley Guest Star Anne Ramsay Guest Star Jenna Fischer Guest Star Chris Pine Guest Star Ann Cusack Guest Star Sean O'Bryan Guest Star J.G. Hertzler Guest Star Elaine Kagan Guest Star Rhys Coiro Guest Star Bahni Turpin Guest Star Monti Sharp Guest Star Kerry Leigh Michaels Guest Star Traber Burns Guest Star Alan Ball Executive Producer