Melissa Benoist Kara Danvers, Supergirl Actor Calista Flockhart Cat Grant Actor Chyler Leigh Alex Danvers Actor Mehcad Brooks James Olsen Actor David Harewood Hank Henshaw Actor Jeremy Jordan Winslow "Winn" Schott Actor Laura Benanti Alura Zor-El , Astra Guest Star Derek Mio Hayashi Guest Star Ben Begley Tobey Guest Star Faran Tahir The Commander Guest Star Owain Yeoman Vartox Guest Star Dean Cain Dr. Jeremiah Danvers Guest Star Helen Slater Eliza Danvers Guest Star Malina Weissman Young Kara Zor-El Guest Star Jordan Mazarati Young Alex Danvers Guest Star Rick Garcia Himself Guest Star Leyna Nguyen Herself Guest Star Robert Gant Zor-El Guest Star Paul Stuart Yale Guest Star Nick Jaine Another Staffer Guest Star Sheila Collins Plane passenger Guest Star Chriss Anglin Pilot Guest Star Kinna McInroe Waitress Guest Star Briana Venskus Agent Vasquez Guest Star Julien Yuen Terrified Teen Guest Star Greg Berlanti Executive Producer, Writer Allison Adler Executive Producer, Writer Andrew Kreisberg Executive Producer, Writer Sarah Schechter Executive Producer Glen Winter Director