Melissa Benoist Kara Danvers, Supergirl Actor Calista Flockhart Cat Grant Actor Chyler Leigh Alex Danvers Actor Mehcad Brooks James Olsen Actor David Harewood Hank Henshaw Actor Jeremy Jordan Winslow "Winn" Schott Actor Peter Facinelli Maxwell Lord Guest Star Jenna Dewan Lucy Lane Guest Star Tristin Mays Paulina Guest Star Chris Jai Alex Guard 1 Guest Star David Salsa Guard 2 Guest Star Henry Czerny Winslow Schott , Toyman Guest Star Isaac Keys Guard 3 Guest Star Bruno Amato Security Guard Guest Star Kavita Patil Doctor Guest Star Scott Alan Smith Chester Dunholtz Guest Star Emma Caulfield Cameron Chase Guest Star Hope Lauren Jane Doe Guest Star Greg Berlanti Executive Producer Allison Adler Executive Producer Andrew Kreisberg Executive Producer Sarah Schechter Executive Producer Yahlin Chang Writer Anna Musky-Goldwyn Writer James DeWille Writer Jamie Babbit Director