Melissa Benoist Kara Danvers, Supergirl Actor Calista Flockhart Cat Grant Actor Chyler Leigh Alex Danvers Actor Mehcad Brooks James Olsen Actor David Harewood Hank Henshaw Actor Jeremy Jordan Winslow "Winn" Schott Actor Peter Facinelli Maxwell Lord Guest Star Blake Jenner Adam Foster Guest Star Hope Lauren Bizarro Guest Star Michael Albala Assistant , Doctor Guest Star Carly Nykanen Employee 1 Guest Star Nick Jaine Employee 2 Guest Star Kent Shocknek Newscaster Guest Star Greg Berlanti Executive Producer Allison Adler Executive Producer Andrew Kreisberg Executive Producer Sarah Schechter Executive Producer Roberto Aguirre-Sacasa Writer Rachel Shukert Writer John Showalter Director