Tony Randall Felix Unger Actor Jack Klugman Oscar Madison Actor Al Molinaro Murray Greshner Guest Star Joan Hotchkis Dr. Nancy Cunningham Guest Star Albert Brooks Rudy Guest Star John Astin Beau Buffingham Guest Star Ryan McDonald Roy Guest Star Christopher Shea Phillip Guest Star Janice Carroll Mrs. Grainger Guest Star Larry Gelman Vinnie Guest Star Richard Stahl Florist Guest Star Nora Marlowe Nurse Guest Star James Millhollin Mr. Humus Guest Star Garry Walberg Speed Guest Star Carole Shelley Gwendolyn Guest Star Bill Quinn Dr. Melnitz Guest Star Ken Swofford Cop Guest Star Monica Evans Cecily Guest Star Beryl Hammond Mary Ann Guest Star Anitra Ford Jeannie Guest Star Garry Marshall Executive Producer, Director, Writer Sheldon Keller Executive Producer Bruce Bilson Director Peggy Elliott Writer Alan Rafkin Director Jerry Paris Director Buddy Tyne Director Hal Cooper Director Charles Rondeau Director Ed Scharlach Writer Albert E. Lewin Writer Jerry Belson Writer Alan Mandel Writer Ron Friedman Writer Lloyd Turner Writer Jack Winter Writer Charles Shyer Writer Gordon Mitchell Writer