Dan Castellaneta Homer Jay Simpson, Barney Gumble, Grampa Simpson, Mayor Joe Quimby, Krusty the Klown, Groundskeeper Willie Voice Julie Kavner Marjorie Bouvier Simpson, Patty Bouvier, Selma Bouvier, Grandma Jackie Bouvier Voice Nancy Cartwright Bartholomew Jo-Jo "Bart" Simpson, Nelson Muntz Voice Yeardley Smith Lisa Marie Simpson Voice Hank Azaria Moe Szyslak, Apu Nahasapeemapetilon, Chief Clancy Wiggum, Dr. Nick Riviera Voice Harry Shearer Charles Montgomery Burns, Waylon Smithers, Principal Seymour Skinner, Ned Flanders, Otto Mann, Scratchy, Kent Brockman, Dr. Julius Hibbert, Reverend Timothy Lovejoy Voice Pamela Hayden Milhouse Van Houten Voice Tress MacNeille Dolph Voice Marcia Wallace Edna Krabappel Guest Voice Elisabeth Moss Gretchen Guest Voice Andrés Cantor Himself, Mafia Guest Voice Eva Longoria Isabel Gutiérrez Guest Voice Chris Edgerly Additional Voices Guest Voice Tavi Gevinson Jenny Guest Voice Maggie Roswell Miss Hoover , Therapist Guest Voice Russi Taylor Martin Prince Guest Voice Kevin Michael Richardson FBI Agent Guest Voice Maurice LaMarche Additional Voices Guest Voice Seth Rogen Himself Guest Voice Will Arnett Deputy Director Gratman Guest Voice James L. Brooks Executive Producer Matt Groening Executive Producer Al Jean Executive Producer Bob Anderson Director Michael Polcino Director Matthew Nastuk Director Mark Kirkland Director Steven Dean Moore Director Chris Clements Director Lance Kramer Director Rob Oliver Director Matthew Faughnan Director Timothy Bailey Director Matthew Schofield Director Chuck Sheetz Director