Charlie Harper (series star CHARLIE SHEEN) is a well-to-do bachelor with a house at the beach, a Jaguar in the garage and an easy way with women. His casual Malibu lifestyle was interrupted when his tightly wound brother, Alan (series star JON CRYER), and Alan's young son, Jake (series star ANGUS T. JONES), came to stay with him. Complicating matters further are Charlie and Alan's narcissistic, emotionally toxic mother, Evelyn (series star HOLLAND TAYLOR--not appearing in this episode), Alan's deeply neurotic ex-wife, Judith (series star MARIN HINKLE), Charlie's domineering, unapologetically blue-collar housekeeper, Berta (series star CONCHATA FERRELL--not appearing in this episode), and Rose (series star MELANIE LYNSKEY), a brilliantly manipulative and vaguely crazy neighbor who had a brief fling with Charlie, remains obsessed with him and is determined to stay in his life by whatever means necessary. Despite the complexities of their lives and their own strained relationship, Charlie and Alan have one thing in common: They both love Jake and want what's best for him. As a result, they manage to create a little family unit that promises to make each one of them a better man.Alan feels hurt when Charlie asks him to stay out of the house while Charlie's buddies come over. Then Alan is further rejected when he learns that his old friends aren't available because they're all at his ex-wife Judith's house for a get-together. Charlie's stalker, Rose, attempts to cheer up lonely, brooding Alan, but only an invitation to join Charlie's elite male support group will make him feel better.Oscar and Golden Globe Award winner SEAN PENN (Mystic River), Grammy Award winner ELVIS COSTELLO, SAG Award nominee HARRY DEAN STANTON (The Green Mile) and BOBBY COOPER (I Am Sam) guest star as themselves (Charlie's support group).