America Ferrera Betty Suarez Actor Eric Mabius Daniel Meade Actor Alan Dale Bradford Meade Actor Tony Plana Ignacio Suarez Actor Ana Ortiz Hilda Suarez Actor Judith Light Claire Meade Actor Christopher Gorham Henry Grubstick Actor Ashley Jensen Christina McKinney Actor Becki Newton Amanda Tanen Actor Michael Urie Marc St. James Actor Mark Indelicato Justin Suarez Actor Rebecca Romijn Alexis Meade Actor Vanessa Williams Wilhelmina Slater Actor Kevin Alejandro Santos Guest Star Lorraine Toussaint Yoga Guest Star Jayma Mays Charlie Guest Star Illeana Douglas Sheila Guest Star Stephanie Faracy Mrs. Tanen Guest Star Kurt Fuller Mr. Tanen Guest Star Alec Mapa Suzuki St. Pierre Guest Star Anastasia Basil Lisa Lapira Guest Star Délé Ogundiran Assistant Editor Guest Star Bob Glouberman Doctor Guest Star Angela Sargeant Nurse Guest Star Kat Sawyer Elaine Klein Guest Star Matt Riedy Bob Klein Guest Star Peter Story Vendor Guest Star MaShae Alderman Girlfriend Guest Star Jim Bannon Telenovela Announcer Guest Voice Silvio Horta Executive Producer, Writer Ben Silverman Executive Producer Salma Hayek Executive Producer Jose Tamez Executive Producer Marco Pennette Writer James Hayman Director