Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Wyatt McClure Billy Sparks Guest Star Matt Hobby Pastor Jeff Guest Star Vernee Watson Nurse Robinson Guest Star Chuck Lorre Executive Producer, Writer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Damir Konjicija Writer Dario Konjicija Writer Michael Zinberg Director