Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Wallace Shawn Dr. Sturgis Guest Star Craig T. Nelson Dale Guest Star Ed Begley Jr. Dr. Linkletter Guest Star Wendie Malick President Hagemeyer Guest Star Julia Pace Mitchell Darlene Wilkins Guest Star Diane Ladd Hortense Guest Star Alan Rachins Vern Guest Star Marla Gibbs Doris Guest Star Paul Mabon Clayton Guest Star Michael Naughton Edwin Guest Star Kevin Will Lucas Guest Star Esteban Dager Chet Guest Star Chuck Lorre Executive Producer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Connor Kilpatrick Writer Yael Glouberman Writer Steve Holland Writer Eric Kaplan Writer Tara Hernandez Writer Melissa Joan Hart Director