Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Craig T. Nelson Dale Guest Star Bill Fagerbakke Jake Guest Star Frank Collison Chet Guest Star Valeri Ross Harriet Guest Star Audrey Wasilewski Joann Guest Star Tony Winters Conductor Guest Star Chuck Lorre Executive Producer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Nick Bakay Writer Nadiya Chettiar Writer Steve Holland Writer Jeremy Howe Writer Connor Kilpatrick Writer Alex Reid Director