Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Wallace Shawn Dr. Sturgis Guest Star Reba McEntire June Guest Star Wendie Malick President Hagemeyer Guest Star Taylor Spreitler Sam Guest Star Grady Lee Richmond Wade Guest Star Matthew Josten Bobby Guest Star Keanush Tafreshi Matt Guest Star Aneasa Yacoub Diane Guest Star Chuck Lorre Executive Producer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Steve Holland Writer Eric Kaplan Writer Jeremy Howe Writer Nadiya Chettiar Writer Connor Kilpatrick Writer Melissa Joan Hart Director