Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Wallace Shawn Dr. Sturgis Guest Star Ed Begley Jr. Dr. Linkletter Guest Star Wendie Malick President Hagemeyer Guest Star Rex Linn Principal Petersen Guest Star Ming-Na Wen Dr. Lee Guest Star Derrick L. McMillon Hal Guest Star Chuck Lorre Executive Producer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Steve Holland Writer Eric Kaplan Writer Nadiya Chettiar Writer Jeremy Howe Writer Connor Kilpatrick Writer Michael Judd Director