Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Wallace Shawn Dr. Sturgis Guest Star Ed Begley Jr. Dr. Linkletter Guest Star Craig T. Nelson Dale Guest Star Emily Osment Mandy Guest Star Chuck Lorre Executive Producer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Nick Bakay Writer Connor Kilpatrick Writer Steve Holland Writer Jeremy Howe Writer Marie Cheng Writer Shiri Appleby Director