Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Ed Begley Jr. Dr. Linkletter Guest Star Dan Byrd Pastor Rob Guest Star Doc Farrow Coach Wilkins Guest Star Grady Lee Richmond Wade Guest Star Chuck Lorre Executive Producer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Steve Holland Writer Eric Kaplan Writer Jeremy Howe Writer Nick Bakay Writer Connor Kilpatrick Writer Shiri Appleby Director