Marcia Gay Harden Dr. Leanne Rorish Actor Boris Kodjoe Dr. Will Campbell Actor Melanie Chandra Dr. Malaya Pineda Actor Harry Ford Dr. Angus Leighton Actor Benjamin Hollingsworth Dr. Mario Savetti Actor Jillian Murray Dr. Heather Pinkney Actor William Allen Young Dr. Rollie Guthrie Actor Luis Guzmán Jesse Sallander Actor Rob Lowe Col. Ethan Willis Actor Tommy Dewey Mike Leighton Guest Star Noah Gray-Cabey Dr. Elliot Dixon Guest Star Emily Tyra Dr. Noa Kean Guest Star Jonna Walsh Whitney Lithwick Guest Star Steven Culp Desmond Leighton Guest Star Annabeth Gish Geraldine Lithwick Guest Star True O'Brien Joy Samton Guest Star Mark L. Young Justin Keller Guest Star Jenna Boyd Vanessa Guest Star Richard Lewis Stewart Guest Star Allan Havey Dennis Guest Star Kevin Jackson Morty Guest Star Nefe Iredia Paramedic 1 Guest Star Chase Gabrielson Paramedic 2 Guest Star Raquel Bell Johnson Paramedic 3 Guest Star Alex Peavey Seth Greer Guest Star Michael Seitzman Executive Producer David Semel Executive Producer Ryan McGarry Executive Producer Marti Noxon Executive Producer Linda Goldstein Knowlton Executive Producer Kayla Alpert Writer David Von Ancken Director