Teri Hatcher Susan Mayer Actor Felicity Huffman Lynette Scavo Actor Marcia Cross Bree Hodge Actor Eva Longoria Gabrielle Solis Actor Nicollette Sheridan Edie Britt Actor Brenda Strong Mary Alice Young Actor James Denton Mike Delfino Actor Doug Savant Tom Scavo Actor Ricardo Antonio Chavira Carlos Solis Actor Andrea Bowen Julie Mayer Actor Shawn Pyfrom Andrew Van De Kamp Actor Joy Lauren Danille Van De Kamp Actor Rachel Fox Kayla Huntington Actor Brent Kinsman Porter Scavo Actor Shane Kinsman Preston Scavo Actor Nathan Fillion Dr. Adam Mayfair Guest Star Kathryn Joosten Mrs. McCluskey Guest Star Chris Carmack Tim Guest Star Dakin Matthews Reverend Sikes Guest Star Jeff Doucette Father Crowley Guest Star Mary K. Devault Nurse Wilkins Guest Star Patricia Place Nun Guest Star Gary Cole Wayne Davis Guest Star Tom Titone Doctor Guest Star Dana Delany Katherine Mayfair Actor Kyle MacLachlan Orson Hodge Actor Zane Huett Parker Scavo Actor Charles Pratt Jr. Executive Producer Marc Cherry Executive Producer Tom Spezialy Executive Producer Michael Edelstein Executive Producer David Grossman Director Alexandra Cunningham Writer Lori Kirkland Baker Writer