Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Dr. Joan Watson Actor Aidan Quinn Capt. Tobias "Toby" Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Dennis Boutsikaris Gerald Lydon Guest Star Christopher Sieber Carter Lydon Guest Star Michael Izquierdo Joshua Lydon Guest Star Steven Hauck Crabtree Guest Star Bennett Bradley Ms. Tompkins Guest Star Jennifer Lim Natasha Kademan Guest Star David Furr Paul Reeves Guest Star Gibson Frazier Raph Keating Guest Star Albert Jones Benny Cordero Guest Star Barbara Miluski Agnieszka Guest Star Aleksander Mici Ludoslaw Guest Star Tom Galantich Brian Watt Guest Star Caroline Strong Ashley Mitchell Guest Star Patricia Conolly Greta Dunwoody Guest Star George Bartenieff Jurgi Guest Star Robert Doherty Executive Producer Sarah Timberman Executive Producer Carl Beverly Executive Producer Michael Cuesta Executive Producer Mark Goffman Writer Seith Mann Writer