Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Dr. Joan Watson Actor Aidan Quinn Capt. Tobias "Toby" Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Vinnie Jones Sebastian Moran Guest Star F. Murray Abraham Daniel Gottlieb Guest Star Roger Aaron Brown John Douglas Guest Star Byron Jennings Phillip Van Der Hoff Guest Star Helen Coxe Hillary Taggart Guest Star Laurence Lau Robert Baumann Guest Star Morgan Weed The Girl With Rainbow Hair Guest Star Mark DiConzo Uniformed Cop Guest Star Tony F. DeVito Convict 1 Guest Star Aaron Berg Convict 2 Guest Star Berto Colon Will Guest Star Kristine Johnson TV Reporter Guest Star Robert Doherty Executive Producer Sarah Timberman Executive Producer Carl Beverly Executive Producer Michael Cuesta Executive Producer Corinne Brinkerhoff Writer Peter Werner Director