Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Rhys Ifans Chairman Guest Star Margaret Colin Natalie Gale Guest Star William Sadler Ian Gale Guest Star Kersti Bryan Haley Tyler Guest Star Elliot Villar Christian Suarez Guest Star Jordan Gelber Dr. Eugene Hawes Guest Star Casey Biggs Alan Becker Guest Star Johanna Day Maureen Tyler Guest Star Kieran Campion Ray McKibben Guest Star Mark Zeisler Arthur Watkins Guest Star Keith Eric Chappelle Parcel Services Drive Guest Star Stephen Friedrich Pet Groomer Employee Guest Star Mike Masters Lead Security Guard Guest Star Robert Doherty Executive Producer Carl Beverly Executive Producer Sarah Timberman Executive Producer Craig Sweeny Executive Producer Bob Goodman Writer John Polson Director