Kelsey Grammer Dr. Frasier Crane Actor, Executive Producer John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Bill Hayes Neil "Sully" Sullivan Guest Star Joe Flaherty Herm Evans Guest Star Catherine Bruhier Cathy Guest Star Leo Marks Frank Guest Star Scott Hamilton Caller 1 Guest Voice Daryl Hannah Caller 2 Guest Voice Olympia Dukakis Caller 3 Guest Voice Keith Carradine Caller Carl Guest Voice Tom McGowan Kenny Daly Guest Star David Angell Executive Producer Peter Casey Executive Producer David Lee Executive Producer Mark Reisman Executive Producer Dan O'Shannon Executive Producer Wil Shriner Director Eric Zicklin Writer