Kelsey Grammer Dr. Frasier Crane Actor, Executive Producer, Director John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Laura Linney Charlotte Guest Star Celia Weston Sue Guest Star Stephen Root Harbin Guest Star Todd Louiso Jonathan Guest Star Cady Huffman Amber Licious Guest Star Blake Lindsley Becky Guest Star David Angell Executive Producer Peter Casey Executive Producer David Lee Executive Producer Mark Reisman Executive Producer Dan O'Shannon Executive Producer Chris Marcil Writer