Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Scott Foley Hank Wiggen Guest Star Bryan Singer Himself Guest Star, Executive Producer Meredith Monroe Lola Guest Star Art LaFleur Warner Fitch Guest Star Salli Richardson-Whitfield Sharon Guest Star Dierdre M. Smith Carol Moffatt Guest Star Timothy McNeil Patient 2 Guest Star Sean Everett Patient 4 Guest Star Richard Swaidan College Student Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer, Writer Keith Gordon Director John Mankiewicz Writer