Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Samantha Mathis Maria Palko Guest Star Eddie Mills Bob Palko Guest Star Peter Birkenhead Vincent Lambert Guest Star Stephanie Erb Charlotte Lambert Guest Star Yareli Arizmendi Lady Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Deran Sarafian Director Thomas L. Moran Writer