Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Mercedes López Renard Marina Hernandez Guest Star Omar Avila Esteban Hernandez Guest Star Stephen Markle Dr. Gooding Guest Star Tiya Sircar Student 1 Guest Star John Bobek Student 2 Guest Star Kathryn Adams Pretty Student 3 Guest Star Ken Luckey Ken Sowinski Guest Star Lucas Ford Pilot Guest Star Eltony Williams Co-Pilot Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer, Director David Shore Executive Producer Bryan Singer Executive Producer Thomas L. Moran Writer Lawrence Kaplow Writer