Lucas Till Angus "Mac" MacGyver Actor Tristin Mays Riley Davis Actor Justin Hires Wilt Bozer Actor Meredith Eaton Matty Webber Actor Levy Tran Desi Nguyen Actor Henry Ian Cusick Russ Taylor Actor Jessie T. Usher Vincent Guest Star Jean Brassard Egor Guest Star Anabelle Acosta Paula Guest Star Enzo D'Agata Luis Guest Star Vannessa Vasquez Jane, Fake Paula Guest Star Juan Pablo Gamboa Gustavo Salazar Guest Star Eugenie Bondurant Susie Guest Star Brittany Pena Doorwoman Guest Star Paul Downs Colaizzo Executive Producer Brett Mahoney Executive Producer David Von Ancken Executive Producer Henry Winkler Executive Producer Lee David Zlotoff Executive Producer Craig S O'Neill Executive Producer Stephanie Hicks Writer Avi Youabian Director