Benedict Cumberbatch Patrick Melrose Actor, Executive Producer Dainton Anderson Thomas Melrose Actor Holliday Grainger Bridget Watson Scott Actor Jessica Raine Julia Actor Blythe Danner Nancy Actor Celia Imrie Kettle Actor Anna Madeley Mary Melrose Actor Sebastian Maltz Young Patrick Melrose Actor Dixie Egerickx Lucy Actor Jonjo O'Neill Seamus Dourke Actor Guy Paul Cousin Henry Actor Eileen Walsh Annette Actor Georgia Goodman Claudine Actor Marcus Smith Robert Melrose Actor Edward Berger Director David Nicholls Writer Edward St. Aubyn Writer Volker Bertelmann Music Stephen Smallwood Producer Rachael Horovitz Executive Producer Michael Jackson Executive Producer Adam Ackland Executive Producer Helen Flint Executive Producer