Paul Abbott Creator William H. Macy Frank Gallagher Actor Emmy Rossum Fiona Gallagher Actor Ethan Cutkosky Carl Gallagher Actor Shanola Hampton Veronica Actor Steve Howey Kev Actor Emma Kenney Debbie Gallagher Actor Cameron Monaghan Ian Gallagher Actor Jeremy Allen White Lip Gallagher Actor Emily Bergl Sammi Gallagher Actor Noel Fisher Mickey Milkovich Actor Dermot Mulroney Sean Pierce Guest Star Sasha Alexander Helene Runyon Guest Star Jenica Bergere Lisa Guest Star Isidora Goreshter Svetlana Guest Star Luca Oriel Derek Guest Star Alan Rosenberg Professor Youens Guest Star