Dominic West Det. James "Jimmy" McNulty Actor John Doman William A. Rawls Actor Frankie Faison Comm. Ervin H. Burrell Actor Wood Harris Avon Barksdale Actor Domenick Lombardozzi Det. Thomas "Herc" Hauk Actor Deirdre Lovejoy Rhonda Pearlman Actor Wendell Pierce Det. William "Bunk" Moreland Actor Lance Reddick Lt. Cedric Daniels Actor Andre Royo Bubbles Actor Sonja Sohn Det. Shakima "Kima" Greggs Actor J.D. Williams Preston "Bodie" Broadus Actor Seth Gilliam Sgt. Ellis Carver Actor Clarke Peters Det. Lester Freamon Actor Jim True-Frost Det. Roland "Prezbo" Pryzbylewski Actor Michael Kenneth Williams Omar Little Actor Corey Parker Robinson Det. Leander Sydnor Actor Robert Wisdom Howard "Bunny" Colvin Actor Aidan Gillen Thomas "Tommy" Carcetti Actor Jamie Hector Marlo Stanfield Actor Chad L. Coleman Dennis "Cutty" Wise Actor Isiah Whitlock Jr. State Sen. R. Clayton "Clay" Davis Actor Glynn Turman Mayor Clarence V. Royce Actor Reg E. Cathey Norman Wilson Guest Star Jermaine Crawford Duquan "Dukie" Weems Guest Star Maestro Harrell Randy Wagstaff Guest Star Julito McCullum Namond Brice Guest Star Mack Wilds Michael Lee Guest Star Gbenga Akinnagbe Chris Partlow Guest Star Hassan Johnson Roland "Wee-Bey" Brice Guest Star Edward Norris Det. Edward Norris Guest Star Delaney Williams Sgt. Jay Landsman Guest Star Brian Anthony Wilson Det. Vernon Holley Guest Star Megan Anderson Jen Carcetti Guest Star Susan Duvall Assistant Principal Marcia Donnelly Guest Star Dravon James Grace Sampson Guest Star Nathan Corbett Donut Guest Star Edward Green Spider Guest Star Brandy Burre Theresa D'Agostino Guest Star Al Brown Maj. Stanislaus Valchek Guest Star Christopher Mann Councilman Anthony "Tony" Gray Guest Star Cleo Reginald Pizana Chief of Staff Coleman Parker Guest Star Frederick Strother State Delegate Odell Watkins Guest Star Sandi McCree De'Londa Brice Guest Star Kwame Patterson "Monk" Metcalf Guest Star Felicia Pearson Felicia "Snoop" Pearson Guest Star Jason Parker Off. Reggie Leddett Guest Star Michael Willis Andy Krawczyk Guest Star Christine Moore Director Ed Burns Writer David Mills Writer