Johnny Galecki Leonard Hofstadter Actor Jim Parsons Sheldon Cooper Actor Kaley Cuoco Penny Actor Simon Helberg Howard Wolowitz Actor Kunal Nayyar Raj Koothrappali Actor Mayim Bialik Amy Farrah Fowler Actor Melissa Rauch Bernadette Rostenkowski Actor Kevin Sussman Stuart Guest Star Laurie Metcalf Mary Cooper Guest Star Jim Meskimen Minister Guest Star Louise Claps Receptionist Guest Star Chuck Lorre Executive Producer, Writer Bill Prady Executive Producer Steven Molaro Executive Producer, Writer Jim Reynolds Writer Maria Ferrari Writer Steve Holland Writer Eric Kaplan Writer Mark Cendrowski Director