Season 4 of the offbeat comedy-drama picks up where the third ended: Agrestic is burning, as is the Botwin house and evidence of Nancy's illegal activities. But the drug-dealing widow doesn't stay to play the fiddle while her hometown goes up in flames. Instead Nancy (Mary-Louise Parker) packs up her family and heads south to Ren Mar, Cal. (near the Tijuana border), to hide out with her estranged, despised father-in-law Len (Albert Brooks in a four-episode story arc) and his comatose mother. Needless to say, the reunion doesn't go well, since Len never cared for his daughter-in-law and isn't very fond of son Andy (Justin Kirk) either. Nancy wastes no time jumping back in the drug game, but soon learns that selling pot in suburbia and joining a cartel in Mexico are two totally different things. She also falls in love with cartel leader Esteban Reyes (Demián Bichir), who just happens to be Tijuana's mayor. But their romance goes to pot when Nancy discovers even she can't stomach trafficking in guns, cocaine...and young women. Her preoccupations make her already shaky skills as a parent go farther downhill, as Silas (Hunter Parrish) becomes involved with a beautiful neighbor (Julie Bowen), and Shane (Alexander Gould) becomes quite a Lothario among the tween crowd. Meanwhile, Andy and Doug (Kevin Nealon) become partners in a human-smuggling operation. And Celia (Elizabeth Perkins), left holding the (dime) bag for Nancy and facing prison time, strikes a deal with Capt. Till (Jack Stehlin) and turns informant.