Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Wallace Shawn Dr. John Sturgis Guest Star Mckenna Grace Paige Guest Star Andrea Anders Linda Guest Star Wyatt McClure Billy Sparks Guest Star Josh Cooke Barry Guest Star Susan Chuang Dr. Lee Guest Star Livia Treviño Paula Guest Star Alfred F. Woodley Shawn Guest Star Chuck Lorre Executive Producer, Writer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Damir Konjicija Writer Dario Konjicija Writer Eric Kaplan Writer Tara Hernandez Writer Rebecca Asher Director