Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Wallace Shawn Dr. John Sturgis Guest Star Ryan Phuong Tam Guest Star Mckenna Grace Paige Guest Star Andrea Anders Linda Guest Star Wyatt McClure Billy Sparks Guest Star Chris Wylde Glenn Guest Star Alex Staggs Stan Guest Star Kevin D'Arcy DMV Employee Guest Star Chuck Lorre Executive Producer, Writer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Tara Hernandez Writer Rebecca Asher Director