Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Wallace Shawn Dr. John Sturgis Guest Star Matt Hobby Pastor Jeff Guest Star Nancy Linehan Charles Peg Guest Star Brian Stepanek Mr. Givens Guest Star Danielle Pinnock Ms. Ingram Guest Star Doc Farrow Assistant Coach Wilkins Guest Star Mary Grill Officer Robin Guest Star Melanie Haynes Felicia Guest Star Heather Olt Waitress Guest Star Michael Christian Alexander Greg Guest Star Zuleyka Silver Selena Guest Star Chuck Lorre Executive Producer, Writer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Damir Konjicija Writer Dario Konjicija Writer Tara Hernandez Writer Jeremy Howe Writer Alex Reid Director