Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Sarah Baker Ms. Hutchins Guest Star Valerie Mahaffey Ms. Macelroy Guest Star Chris Wylde Glenn Guest Star Winifred Freedman Luann Guest Star London Chesire Marcus Guest Star Chuck Lorre Executive Producer Steven Molaro Executive Producer Todd Spiewak Executive Producer Eric Kaplan Writer Tara Hernandez Writer Steven Holland Writer Maria Ferrari Writer Connor Kilpatrick Writer Jaffar Mahmood Director