Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Wallace Shawn Dr. Sturgis Guest Star Craig T. Nelson Dale Guest Star Doc Farrow Coach Wilkins Guest Star Rex Linn Principal Petersen Guest Star Valerie Mahaffey Ms. Macelroy Guest Star Brian Stepanek Mr. Givens Guest Star Danielle Pinnock Ms. Ingram Guest Star Gerald Downey Jim Guest Star Chuck Lorre Executive Producer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Eric Kaplan Writer Maria Ferrari Writer Jeremy Howe Writer Steve Holland Writer Connor Kilpatrick Writer Chris Koch Director