Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Rex Linn Principal Petersen Guest Star Doc Farrow Coach Wilkins Guest Star Caleb Emery Darren Guest Star Ivan Mok Oscar Guest Star Maddy Caddell Abby Guest Star Drew Powell Roy Guest Star Maurice Hall Floyd Guest Star Sophia Coto Heather M. Guest Star Reagan Marum Heather B. Guest Star Chuck Lorre Executive Producer Steven Molaro Executive Producer, Writer Todd Spiewak Executive Producer Jeremy Howe Writer Marie Cheng Writer Steve Holland Writer Nick Bakay Writer Connor Kilpatrick Writer Jaffar Mahmood Director