Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Melissa Peterman Brenda Sparks Guest Star Wyatt McClure Billy Sparks Guest Star Emily Osment Mandy Guest Star Alex Reid Director Chuck Lorre Executive Producer Steven Molaro Executive Producer Todd Spiewak Executive Producer Nick Bakay Writer Nadiya Chettiar Writer Yael Glouberman Writer Steve Holland Writer