Chuck Lorre Creator, Executive Producer Steven Molaro Creator, Executive Producer, Writer Iain Armitage Sheldon Actor Zoe Perry Mary Actor Lance Barber George Sr. Actor Annie Potts Meemaw Actor Montana Jordan Georgie Actor Raegan Revord Missy Actor Jim Parsons Adult Sheldon Narrator, Executive Producer Matt Hobby Pastor Jeff Actor Emily Osment Mandy Actor Ed Begley Jr. Dr. Linkletter Guest Star Melissa Peterman Brenda Guest Star Dan Byrd Pastor Rob Guest Star Jason Rogel Nigel Guest Star Francesca Xuereb Shannon Guest Star Todd Spiewak Executive Producer Steve Holland Writer Nick Bakay Writer Yael Glouberman Writer Eric Kaplan Writer Nadiya Chettiar Writer Beth McCarthy-Miller Director