Marla Gibbs Mary Jenkins Actor Hal Williams Lester Jenkins Actor Alaina Reed-Hall Rose Lee Holloway Actor Jackée Harry Sandra Clark Actor Regina King Brenda Jenkins Actor Helen Martin Pearl Shay Actor Curtis Baldwin Calvin Dobbs Actor Kia Goodwin Tiffany Halloway Actor Benard Ighner Guest Star Reni Santoni Guest Star Wesley Thompson Guest Star Eve Smith Guest Star Nathaniel Taylor Guest Star Rod Gist Guest Star Wally Taylor Guest Star Frank Jenkins Guest Star Whitman Mayo Guest Star Stephen Tobolowsky Guest Star Peter Kwong Guest Star David Chung Guest Star