Gary Sinise Det. Mack "Mac" Taylor Actor Sela Ward Jo Danville Actor Carmine Giovinazzo Det. Danny Messer Actor Hill Harper Dr. Sheldon Hawkes Actor Eddie Cahill Det. Donald Flack, Jr. Actor Anna Belknap Det. Lindsay Monroe Messer Actor A.J. Buckley Adam Ross Actor Robert Joy Dr. Sid Hammerback Actor Natalie Martinez Detective Jamie Lovato Guest Star Bill Smitrovich Guest Star David Fumero Benny Madera Guest Star Juan Gabriel Pareja Guest Star Sy Franco Carmen Vega Guest Star Jorge-Luis Pallo Guest Star Orson Chaplin Guest Star Link Baker Construction Worker Guest Star Alastair Bayardo Sleazy Man Guest Star Gregory Gordon Drug Addict Guest Star Julie McKinnon A , V Lab Tech Guest Star Jerry Bruckheimer Executive Producer Carol Mendelsohn Executive Producer Ann Donahue Executive Producer Anthony Zuiker Executive Producer Danny Cannon Executive Producer Andrew Lipsitz Executive Producer Adam Targum Writer Sam Hill Director