Teri Hatcher Susan Mayer Actor Felicity Huffman Lynette Scavo Actor Marcia Cross Bree Hodge Actor Eva Longoria Gabrielle Solis Actor Nicollette Sheridan Edie Britt Actor Alfre Woodard Betty Applewhite Actor Brenda Strong Mary Alice Young Actor James Denton Mike Delfino Actor Doug Savant Tom Scavo Actor Ricardo Antonio Chavira Carlos Solis Actor Mark Moses Paul Young Actor Richard Burgi Karl Mayer Actor Roger Bart George Williams Actor Cody Kasch Zach Young Actor Andrea Bowen Julie Mayer Actor Shawn Pyfrom Andrew Van De Kamp Actor Joy Lauren Danille Van De Kamp Actor Mehcad Brooks Matthew Applewhite Actor Jesse Metcalfe John Rowland Actor Zane Huett Parker Scavo Actor Shirley Knight Phyllis Van De Kamp Guest Star Harriet Sansom Harris Felicia Tilman Guest Star Joely Fisher Nina Fletcher Guest Star Alejandro Patiño Ralph Guest Star Rende Rae Norman Mrs. Novak Guest Star Charlie Babcock Stu Durber Guest Star Harry S. Murphy Headmaster Lentz Guest Star Kurt Fuller Detective Barton Guest Star Charles Pratt Jr. Executive Producer Marc Cherry Executive Producer Tom Spezialy Executive Producer, Writer Michael Edelstein Executive Producer Ellen Herman Writer Arlene Sanford Director