Dominic Minghella Creator Martin Clunes Dr Martin Ellingham Actor Caroline Catz Louisa Ellingham Actor Ian McNeice Bert Large Actor Jessica Ransom Morwenna Newcross Actor John Marquez PC Penhale Actor Joe Absolom Al Large Actor Selina Cadell Mrs Tishell Actor Eileen Atkins Ruth Ellingham Actor Rosalie Craig Lorna Argyll Guest Star Angela Curran Caitlin Morgan Guest Star Rosie Ede Mel Hendy Guest Star Buffy Davis Pippa Woodley Guest Star Jeremy Swift Miles Green Guest Star Ruth Gemmell Shirley Knott Guest Star John Hollingworth Prof. Sam Bradman Guest Star Olivia Darnley Amy Boyd Guest Star Hamza Jeetooa Dr Khan Guest Star Elliott Blake James Henry Guest Star Melanie Downs Postwoman Steph Guest Star Nigel Cole Director Mark Crowdy Executive Producer Philippa Braithwaite Producer Colin Towns Original Music