Jane Seymour Dr. Michaela "Mike" Quinn Actor Joe Lando Byron Sully Actor Chad Allen Matthew Cooper Actor Shawn Toovey Brian Cooper Actor Jessica Bowman Colleen Cooper Actor John Schneider Daniel Simon Actor Geoffrey Lower Rev. Timothy Johnson Actor Orson Bean Loren Bray Actor Jim Knobeloch Jake Slicker Actor William Shockley Hank Claggerty Actor Barbara Babcock Dorothy Jennings Actor Larry Sellers Cloud Dancing Actor Alex Meneses Teresa Morales Actor Alexandria McKenzie Calabrese Actor Zach Galligan Guest Star Linda Hawkins Guest Star Layne Miller Guest Star Alan Brooks Guest Star Carmen Ashby Guest Star Beth Sullivan Executive Producer Carl Binder Executive Producer, Writer James Keach Director