Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Dr. Joan Watson Actor Aidan Quinn Capt. Tobias "Toby" Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Susan Pourfar Emily Hankins Guest Star Josh Hamilton Drew Gardner Guest Star Geneva Carr Rebecca Burrell Guest Star Andre Royo Thaddeus Guest Star Jim True-Frost Anson Samuels Guest Star Timothy Sekk Ken Guest Star Victoria Cartagena Hope Guest Star Roxanna Hope Callie Burrell Guest Star Penny McNamee Vivian Tully Guest Star Kenneth Tigar Philip Armistead Guest Star Jimmy Palumbo Security Guard Guest Star Robert Doherty Executive Producer Sarah Timberman Executive Producer Carl Beverly Executive Producer Michael Cuesta Executive Producer Brian Rodenbeck Writer Jerry Levine Director